最新医学新闻 | Dietary Fiber and Lung Health: Eat Well, Breath Easy

Tim Newman2016/01/28

膳食纤维摄入量较高可能与更好的肺功能相关,研究表明高纤维饮食或可降低气道受限和慢性阻塞性肺疾病(COPD)的风险。尽管尚不能确立因果关系,但现有证据提示纤维通过抗炎作用和调节肠道菌群等机制对肺部健康产生潜在益处。

关键要点

  • 一项基于NHANES数据的研究发现,每日摄入至少17.5克膳食纤维的人群中,68.3%肺功能正常,显著高于低纤维摄入组的50.1%。
  • 高纤维饮食与较低的气道受限率相关(14.8% vs 29.8%),即使在调整吸烟、体重和社会经济因素后仍具统计学意义。
  • 膳食纤维可能通过其抗炎特性(如降低C反应蛋白)和调节肠道菌群来间接支持肺部健康。
  • 此前多项研究也表明高纤维摄入与更高肺功能、更低COPD风险及减少呼吸系统相关死亡率存在关联。
  • 研究人员建议未来公共卫生指南可考虑将高纤维饮食作为预防肺病的安全且低成本策略。

小白老师说:Could eating more fruits and vegetables keep your lungs healthy? Research published this week in the Annals of the American Thoracic Society demonstrates that a diet high in fiber might reduce the chance of developing lung disease.

Written by Tim Newman

Lung disease is a major issue in America and the world at large. Chronic obstructive pulmonary disease (COPD) is the third biggest killer on a global scale.

Despite this fact, ways to curtail and minimize risks to the lungs are few and far between.

The only major recommendation to mitigate the chances of COPD is to stop smoking.

A recent study was carried out at the University of Nebraska Medical Center by Corrine Hanson; she and her team poured over data from the National Health and Nutrition Examination Surveys (NHNES) on the hunt for nutritional clues into lung health.

The NHNES was organized and conducted by the Centers for Disease Control and Prevention (CDC) and involves data from 1,921 people aged 40-70.

The participants completed a survey asking questions about diet and lifestyle; each session also involved a physical examination, making the NHNES a unique and incredibly useful data set.

Dietary fiber and health

Eating high-fiber foods, including vegetables, fruits and grains, already has proven health benefits. Fiber can help us maintain a healthy weight by keeping us feeling fuller for longer; fiber regularizes bowel movements, lowers cholesterol and can reduce the risk of diabetes and heart disease.

The Nebraska team wanted to see if a high dietary intake of fiber would also make a positive difference to lung health. To this end, they split the NHNES data by the amount of fiber consumed. The upper quartile consisted of people who ate at least 17.5 g of fiber per day and the lower quartile consumed less than 10.75 g.

The team adjusted for factors including socioeconomic status, smoking, weight, demographic and health factors before beginning the analysis.

Fiber and lung health

Even after the data had been adjusted for the factors listed above, the lungs of the individuals in the high-fiber group fared better than those in the lowest quartile. Of the high fiber consumers, 68.3% had normal lung function compared with 50.1% of the lower quartile; only 14.8% of the high fiber consumers had airway restriction, compared with 29.8% in the lower quartile.

The results infer that sticking to a high-fiber diet will do your lungs a favor.

Of course, these results alone cannot prove cause and effect; additionally, the authors are quick to note that they did not adjust for physical activity, and they could not analyze fiber’s impact on lung function over time.

Having said that, their findings add weight to previous investigations. A study using data from the Atherosclerosis Risk in Communities study found that individuals who consumed the most dietary fiber had the highest lung function, compared with those who consumed the least.

Another previous study found a relationship between higher fiber intake and a lower risk of COPD; another still demonstrated that higher fiber consumption was associated with a 40-50% reduction in respiratory-related deaths.

Hanson hopes that, if the findings are further replicated, public health bodies will be able to “target diet and fiber as safe and inexpensive ways of preventing lung disease.”

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Could eating more fruits and vegetables keep your lungs healthy?

How could fiber benefit the lungs?

If fiber truly is a protector of the lungs, what mechanisms might it use? The authors believe that it might be due, at least in part, to the proven anti-inflammatory properties of dietary fiber.

Inflammation underlies a number of lung diseases, and a reduction in this response might be enough to improve the lung’s overall health. C-reactive protein is believed to be important in the inflammation response and does appear to be reduced in people with high-fiber diets.

Another potential mechanism involves fiber’s ability to change the makeup of the gut flora. These changes could protect the body from infections and release lung-protective agents, including neutrophils.

Research into lung health and diet will no doubt continue to throw out intriguing and, perhaps, unexpected results. The evidence for fiber and its protective role seems to be mounting. But, either way, eating additional fruits and vegetables can never be a bad thing.

Medical News Today recently covered research showing that diets high in soluble fiber might help prevent weight gain.

常见问题

高纤维饮食能预防肺病吗?

目前研究显示高纤维摄入与更好的肺功能和更低的气道受限风险相关,但尚不能证明直接因果关系;不过其抗炎和调节肠道菌群的作用可能对肺部有保护效应。

每天需要摄入多少膳食纤维才对肺有益?

该研究中,高纤维组定义为每日摄入至少17.5克纤维,而低纤维组低于10.75克;高摄入组肺功能明显更优。

哪些食物富含对肺有益的膳食纤维?

蔬菜、水果和全谷物是膳食纤维的主要来源,这些食物已被证实有助于整体健康,并可能间接支持肺部功能。

这项研究是否考虑了吸烟等混杂因素?

是的,研究已调整吸烟、体重、社会经济地位和人口学特征等因素,但未纳入体力活动数据,也未追踪长期肺功能变化。

参考资料

Dietary Fiber Intake Is Associated with Improved Lung Function in the General Population

https://doi.org/10.1513/AnnalsATS.201603-210OC

发表于《美国胸科学会年鉴》,由内布拉斯加大学医学中心Corrine Hanson团队基于NHANES数据开展。

Atherosclerosis Risk in Communities (ARIC) Study on Fiber and Lung Function

既往研究显示高纤维摄入者肺功能更高,具体文献未在原文中提供完整引用。

National Health and Nutrition Examination Survey (NHANES)

https://www.cdc.gov/nchs/nhanes/

由美国疾控中心(CDC)主导的全国性健康与营养调查,本研究使用其1,921名40-70岁参与者的数据。