最新医学新闻 | 年轻时多吃高纤维食物可以降低患乳腺癌的风险
摘要: 一项发表于《儿科学》期刊的研究表明,青少年期和成年早期摄入高纤维食物与女性乳腺癌风险降低显著相关,尤其是来自水果和蔬菜的膳食纤维。研究发现,每天多摄入10克纤维可使乳腺癌风险降低13%,青春期高纤维摄入更与绝经前乳腺癌风险下降24%相关。
- 青春期和成年早期高纤维饮食与乳腺癌总体风险降低12%-19%相关。
- 每天额外摄入10克膳食纤维(如一个苹果加两片全麦面包)可降低13%的乳腺癌风险。
- 来自水果和蔬菜的纤维对降低乳腺癌风险效果最显著。
- 高纤维饮食可能通过降低血液中雌激素水平来减少乳腺癌风险,因雌激素是该病的重要风险因素。
- 乳腺组织在青少年时期对致癌物和抗癌物质特别敏感,此阶段的饮食可能影响未来癌症风险。
小白老师说:High intake of fiber-rich foods in adolescence and early adulthood could reduce women’s risk for breast cancer. This is the conclusion of a new study published in the journal Pediatrics.
High Fiber Intake When Young May Lower Women’s Breast Cancer Risk
Written by Honor Whiteman
According to lead author Maryam Farvid, visiting scientist at Harvard T.H. Chan School of Public Health, most previous studies assessing the link between fiber intake and breast cancer risk have been “non-significant.”
She notes that none of these studies have looked at diet during adolescence and young adulthood - a period that appears to be closely associated with breast cancer risk factors.
To address this research gap, the team analyzed data of 90,534 women who were part of the Nurses’ Health Study II.
Information about food intake was gathered through a dietary questionnaire completed in 1991 - when the women were aged 27-44 - and every 4 years thereafter. In 1998, the women completed another questionnaire asking them about their food intake in high school.

Farvid and colleagues analyzed the women’s fiber intake using the dietary data, and they also assessed breast cancer incidence among the women.
Each 10 g of daily dietary fiber linked to 13% lower breast cancer risk
Compared with women who had low fiber intake in early adulthood, those who had high fiber intake were found to be at 12-19% lower overall breast cancer risk.
High fiber intake during adolescence was associated with an overall 16% lower risk of breast cancer and a 24% lower risk of premenopausal breast cancer.
Additionally, the team found that the more fiber consumed in early adulthood, the lower the breast cancer risk; every additional 10 g of fiber consumed each day - the equivalent to one apple and two slices of whole wheat bread - was linked to a 13% lower breast cancer risk.
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Fiber that came from fruits and vegetables was associated with the strongest reduction in breast cancer risk.
While the team is unclear exactly why a fiber-rich diet appears to lower the risk of breast cancer, they hypothesize that high-fiber foods may help to reduce high estrogen levels in the blood; such levels are a major risk factor for the disease.
After skin cancer, breast cancer is the most common cancer among American women; this year, more than 246,000 women in the US are expected to be diagnosed with the disease.
Based on their findings, the team suggests that young women may want to think about increasing their fiber intake in order to help reduce their risk of breast cancer.
Commenting on the results, senior author Walter Willett, Fredrick John Stare professor of epidemiology and nutrition at Harvard, says:
“From many other studies we know that breast tissue is particularly influenced by carcinogens and anti-carcinogens during childhood and adolescence. We now have evidence that what we feed our children during this period of life is also an important factor in future cancer risk.”
A high-fiber diet may not only reduce breast cancer risk. A study recently reported by Medical News Today suggests that a diet rich in fiber may lower the likelihood of lung disease.
Fast facts about breast cancer
1. Around 1 in 8 women in the US will develop invasive breast cancer in their lifetime
2. This year, around 40,450 women are expected to die from the disease
3. There are currently around 2.8 million breast cancer survivors in the US.
常见问题
为什么年轻时吃高纤维食物能降低乳腺癌风险?
研究推测高纤维食物可能有助于降低血液中的雌激素水平,而高雌激素是乳腺癌的主要风险因素之一。
每天需要摄入多少纤维才能看到保护作用?
研究显示,每天多摄入10克膳食纤维(相当于一个苹果加两片全麦面包)就与乳腺癌风险降低13%相关。
哪种来源的纤维对预防乳腺癌最有效?
来自水果和蔬菜的膳食纤维与乳腺癌风险降低的关联最为显著。
这项研究的数据来自哪里?
研究分析了护士健康研究II(Nurses' Health Study II)中90,534名女性的饮食和健康数据,包括她们在高中及成年早期的膳食信息。
参考资料
Fiber intake during adolescence and early adulthood and risk of breast cancer
↗发表于《Pediatrics》期刊的原始研究,由哈佛大学公共卫生学院科学家主导。
Nurses' Health Study II
本研究使用的大型前瞻性队列数据来源,由哈佛大学开展。