Upper Endoscopy Overused in Patients with Acid Reflux

Kelly Fitzgerald2016/09/18英语学习

摘要: 上消化道内镜检查(Upper endoscopy)在胃食管反流病(GERD)患者中常被过度使用;新研究指出,除非伴有吞咽困难、体重减轻、贫血等警示症状,否则大多数仅有烧心症状的患者无需接受该检查。

  • 仅表现为典型胃食管反流症状(如烧心或反酸)的患者通常不需要进行上消化道内镜检查。
  • 美国医师学会(ACP)建议,50岁以下男性及所有年龄段女性若仅有烧心症状,不应常规接受内镜筛查,因其食管癌风险极低。
  • 对于50岁以上男性,仅当存在多个巴雷特食管风险因素(如夜间反流、腹型肥胖、吸烟等)时才考虑内镜筛查。
  • 初次内镜检查未发现巴雷特食管或食管癌者,不推荐定期重复检查。
  • 内镜过度使用不仅增加不必要的医疗费用(单次超800美元),还可能导致并发症和后续无益干预。

小白老师说:Most patients experiencing heartburn, also called acid reflux, do not need the commonly used screening procedure known as endoscopy unless there are other critical symptoms exhibited, suggests new research in a clinical policy paper published in the journal Annals of Internal Medicine.

Heartburn is one of the most common issues leading people to seek a doctor’s advice. Physicians often use upper endoscopy to diagnose and control gastroesophageal reflux disease (GERD), as it can increase the risk of esophageal cancer.

Upper endoscopy involves putting a long, flexible tube down into the throat and taking pictures of the esophagus, stomach and other parts of the gastrointestinal tract.

David L. Bronson, MD, FACP, president, ACP, said:

“The evidence indicates that upper endoscopy is indicated in patients with heartburn only when accompanied by other serious symptoms such as difficult or painful swallowing, bleeding, anemia, weight loss, or recurrent vomiting. The procedure is not an appropriate first step for most patients with heartburn.”

The American College of Physicians (ACP) recommends that screening using upper endoscopy should not be regularly conducted in women of any age or in men under the age of 50 with heartburn because the prevalence of cancer is extremely low in these populations.

Upper endoscopy is generally used for patients with acid reflux who do not respond to medicine (proton pump inhibitors) to decrease gastric acid production for a period of four to eight weeks, or who have in the past experienced narrowing or constricting of the esophagus with repeated painful or tough swallowing.

For men over 50 years of age, upper endoscopy screening should be used when multiple risk factors for Barrett’s esophagus are seen. They include the following:

  • nocturnal reflux symptoms
  • hernia
  • tobacco use
  • fat within abdominal cavity
  • elevated body mass index

If the first screening test for Barrett’s esophagus or esophageal cancer is negative, recurrent periodic upper endoscopy is not suggested.

For patients who have Barrett’s esophagus, upper endoscopy is recommended every three to five years. Continual endoscopic tests are suggested for patients with low- or high-grade dysplasia, because of the increased risk of developing cancer.

Doctors should make use of education programs to inform patients about up-to-date and effective standards of care. Medication is ideal to decrease gastric acid creation in the majority of patients with classic GERD symptoms like regurgitation or heartburn.

Dr. Bronson explains, “inappropriate use of upper endoscopy does not improve the health of patients, exposes them to preventable harms, may lead to additional unnecessary interventions, and results in unnecessary costs with no benefit.”

Certain components that play a part in overuse of upper endoscopy include the following:

  • patient and caregiver expectations
  • medico-legal liability concerns
  • professional medical organizations

Extra and pointless expenses include the procedure itself (excess of $800 per exam) when it is recommended, as well as the flood of costs from follow up tests because of an original misdiagnosis.

Also, previous research has told us there may be severe complications that occur with endoscopy. These complications can result in additional hospital visits, increased costs, and potentially life-threatening situations.

常见问题

哪些胃食管反流患者需要做上消化道内镜?

仅当患者出现吞咽困难、疼痛性吞咽、体重减轻、贫血、反复呕吐或对质子泵抑制剂治疗无效等症状时,才建议进行上消化道内镜检查。

为什么50岁以下男性和女性通常不需要内镜筛查?

因为这些人群中食管癌的患病率极低,常规内镜筛查缺乏临床获益,反而可能带来不必要的风险和费用。

确诊巴雷特食管后需要多久复查一次内镜?

无异型增生的巴雷特食管患者建议每3至5年复查一次内镜;若存在低级别或高级别异型增生,则需更频繁监测。

内镜过度使用会带来哪些风险?

包括不必要的医疗支出、假阳性结果引发的额外检查、操作相关并发症(如穿孔或出血),甚至可能危及生命。

参考资料

American College of Physicians Clinical Guidelines on Upper Endoscopy for GERD

发表于《Annals of Internal Medicine》的临床政策文件,由美国医师学会(ACP)发布,指导GERD患者内镜使用的适应症。